Uranium Powder SDS

Revision Date: 02/08/2023


Name: Uranium

Synonyms: Uranium Powder


IBI Labs

3495 N. Dixie Hwy. Unit # 8

Boca Raton, FL 33431

Tel: 561-826-0061 Fax: 561-892-8450

Emergency Telephone Numbers


USA & Canada contact number: 1-800-535-5053

International contact number: 1-352-323-3500


OSHA Hazards: Highly toxic by inhalation, highly toxic by ingestion.

Hazards Classification

Target Organs: Kidney, liver, lungs, brain.

GHS Classification:

Acute toxicity, Oral (Category 2)

Acute toxicity, Inhalation (Category 2)

Specific target organ toxicity – repeated exposure (Category 2)

Acute aquatic toxicity (Category 2)

Chronic aquatic toxicity (Category 2)

GHS Label elements, including precautionary statements:


Signal word: Danger

Hazard Statements

H300 + H330 Fatal if swallowed or inhaled.

H373 May cause damage to organs through prolonged or repeated exposure.

H411 Toxic to aquatic life with long lasting effects.

H250 Catches fire spontaneously if exposed to air.

Precautionary statements:

P220 Keep/store away from clothing/combustible materials.

P260 Do not breath dust/fume/gas/mist/vapors/spray.

P264 Wash hands thoroughly after handling.

P273 Avoid release to environment.

P284 Wear respiratory protection.

P310 Immediately call poison center or doctor/physician.

Other Hazards


NFPA Rating

Health hazard: 3

Fire 0

Reactivity 3

CERCLA Ratings (SCALE 0-3)

Health U

Fire 0

Reactivity 3

Persistence 3


Chemical Name: Uranium (U) 100%.

CAS RN: [7440-61-1]

Chemical Family: Metal


  • Appearance: Grayish white, dense, silvery.
  • Molecular Formula: U
  • Boiling Point: 3818°C
  • Melting Point: 1132°C
  • Specific Gravity: 19.0
  • Water Solubility: Insoluble.
  • Solvent Solubility: Soluble in acetone, in acids and insoluble in alkalies and alcohol.

The half-lives of the various uranium isotopes are as follows:

233U = 1.59 X 105 y; 234U = 2.47 X 105 y; 235U = 7.04 X 108 y; 236U = 2.39 X 107 y;

238U = 4.51 X 109 y.

The specific activities of the various uranium isotopes are as follows:

233U = 3.6 X 102 MBq/g (9.7 X 10-3 Ci/g)

234U = 2.3 X 102 MBq/g (6.2 X 10-3 Ci/g)

235U = 7.8 X 10-2 MBq/g (2.1 X 10-6 Ci/g)

236U = 2.3 MBq/g (6.3 X 10-5 Ci/g)

238U = 1.2 X 10-2 MBq/g (3.3 X 10-7 Ci/g)

See 10 CFR Chapter 1, Pt. 71, Appendix A.


Indication of immediate medical attention:

  • In all routes of exposure, seek medical treatment immediately.
  • Medical problems take priority over radiologic concerns.
  • See treatment/first-aid measures below.


  • Remove to fresh air.
  • If breathing becomes difficult, call a physician.


  • If swallowed, wash out mouth with water provided person is conscious.
  • Call a physician.

Skin contact: In case of contact, immediately wash skin with soap and copious amounts of water.

Eye contact:

  • Flush with copious amounts of water for at least 20 minutes.
  • Assure adequate flushing by separating the eyelids with fingers.
  • Call a physician.

Most Important Symptoms, Acute and Delayed

  • Uranium is a nephrotoxin, damaging the kidneys.
  • Uranium is a skin, eye, and mucous membrane irritant.


Suitable extinguishing media: Dry chemical, carbon dioxide, water spray, or regular foam.

Fire and explosion hazard:

  • Dangerous fire hazard when exposed to heat or flame.
  • Dangerous explosion hazard when exposed to heat or flame.
  • Pyrophoric.

Hazardous combustion products: Thermal decomposition may release toxic and hazardous gases.

Special protective equipment and precautions for firefighters:

  • Move container from fire area if you can do it without risk.
  • Wear self-contained breathing apparatus if necessary.
  • Apply cooling water to sides of containers exposed to flames until well after fire is out.
  • Do not move damaged containers; move undamaged containers out of fire zone.
  • For massive fire in cargo area, use unmanned hose holder or monitor nozzles.
  • Contact the local, State, or Department of Energy radiological response team.
  • Use suitable agent for surrounding fire.
  • Cool containers with flooding amounts of water, apply from as far a distance as possible.
  • Avoid breathing dusts or vapors, keep upwind.
  • Keep unnecessary people out of area until declared safe by radiological response team.


Personal precautions and protective equipment:

  • Avoid contact with eyes, skin, and clothing.
  • Avoid breathing dust.
  • Wear respiratory protection, gloves, over garment, and goggles.
  • Evacuate personnel to safe areas.

Emergency procedures and materials for containment and clean-up:

  • Do not touch damaged containers or spilled material.
  • Damage to outer container may not affect primary inner container.
  • For small liquid spills, take up with sand, earth, or other absorbent material.
  • For large spills, dike far ahead of spill for later disposal.
  • Keep unnecessary people at least 150 feet upwind; greater distances may be necessary if advised by qualified radiation authority.
  • Isolate hazard area and deny entry.
  • Enter spill area only to save life, limit entry to shortest possible time.
  • Detain uninjured persons and equipment exposed to radioactive material until arrival or instruction of qualified radiation authority.
  • Delay cleanup until arrival or instruction of qualified radiation authority.


Precautions for safe handling:

  • Avoid contact with skin and eyes.
  • Wash hands thoroughly after handling.

Conditions for safe storage:

  • Store in radioactive materials area.
  • Keep container tightly closed.
  • Store separately from incompatible materials.
  • Observe all Federal, state, and local regulations when storing this substance.


Exposure Limits


  • 0.2 mg/m3 OSHA TWA; 0.6 mg/m3 OSHA STEL
  • 0.2 mg/m3 ACGIH TWA; 0.6 mg/m3 ACGIH STEL
  • 0.2 mg/m3 NIOSH Recommended TWA; 0.6 mg/m3 NIOSH Recommended STEL

Engineering Controls

Occupational exposure to radioactive substances must adhere to standards established by the Occupational Safety and Health Administration., 29 CFR 1910.96, and/or the Nuclear Regulatory Commission, 10 CFR Part 20. IF purchased by DOE or DOE governed facilities subject to 10 CFR 835. Subject to foreign entity radiation protection regulations.


  • At a minimum, provide local exhaust or process enclosure ventilation.
  • One method of controlling external radiation exposure is to provide adequate shielding.
  • The absorbing material used, and the thickness required to attenuate the radiation to acceptable levels depends on the type of radiation, its energy, the flux, and the dimensions of the source.

Alpha particles: For the energy range of alpha particles usually encountered, a fraction of a millimeter of any ordinary material or a few inches of air is sufficient for absorbency. Rubber, cardboard or any such material will suffice.

Beta particles: Beta particles are more penetrating than alpha and require more shielding. Materials composed mostly of elements of low atomic number such as acrylic, aluminum, and thick rubber are most appropriate for the absorption of beta particles.

With high-energy beta radiation from large sources, Bremsstrahlung (X-ray production) contribution may become significant, and it may be necessary to provide additional shielding of high atomic weight material, such as lead, to attenuate the Bremsstrahlung radiation. In the quantities shipped, Certified Reference Materials will not emit significant amounts of beta particles.

Gamma rays: The most suitable materials shielding gamma radiation are lead and iron. Normal and depleted uranium is not normally considered gamma emitters. In the quantity shipped, enriched Certified Reference Materials will pose only a negligible gamma hazard.

Personal Protective Equipment

Clothing, glove, and eye protection equipment will provide protection against alpha particles.

Eye protection: Employee must wear appropriate eye protection that will not allow the introduction of particles into the eyes. Contact lenses should not be worn.

Clothing: Disposable over-garments, including head coverings and foot covering, should be worn by any employee engaged in handling any radioactive substance. These garments are also recommended even if the employee is working with a “glovebox” containment system.

In the event of an accident, full protective clothing will be necessary.

Gloves: Employee must wear appropriate protective gloves to prevent contact with this substance. Used gloves may be contaminated and should be disposed of as radioactive waste.

Respirator: The following respirators and maximum use concentrations are recommendations by the U.S. Department of Health and Human Services, NIOSH pocket guide to chemical hazards; NIOSH criteria documents or by the U.S. Department of Labor, 29 CFR 1910 Subpart Z.

The specific respirator selected must be based on contamination levels found in the workplace, must not exceed the working limits of the respirator, and be jointly approved by the National Institute for Occupational Safety, and Health and the Mine Safety and Health Administration (NIOSH-MSHA).

URANIUM, Insoluble compounds (As U)

At Any Detectable Concentration: Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode.

Any supplied air respirator that has a full facepiece and is operated in a pressure-demand, or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand, or other positive-pressure mode.

Escape any air-purifying, full-facepiece respirator with a high-efficiency particulate filer.

Any appropriate escape-type, self-contained breathing apparatus.

For Firefighting and Other Immediately Dangerous to Life or Health Conditions

Any self-contained breathing apparatus that has a full facepiece respirator with a high-efficiency particulate filter.

Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode.

Potential Health Effects


  • Short term exposure: may cause lack of appetite, nausea, vomiting, diarrhea, dehydration, kidney damage, blood in the urine, jaundice, weakness, drowsiness, incoordination, twitching, sterility, blood disorders, convulsions, and shock. Exposure to radioactive substances increases one’s risk of developing cancer.
  • Long term effects: In addition to effects from short-term exposure, anemia, cataracts, and lung damage may occur.


  • Short term exposure: No information available on significant adverse effects.
  • Long term effects: May cause skin irritation.


  • Short term exposure: May cause irritation. Additionally, eye damage, including ulcerations, may occur.
  • Long term effects: It is unlikely that long term eye contact would occur as the effects of short-term exposure, over a period, would result in serious eye damage. However, if long term exposure did occur, cataracts may also occur.


  • Short term exposure: May cause kidney damage. May cause increased cancer risk.
  • Long term effects: Same effects as short-term exposure.

Carcinogen Status





Chemical Stability:

  • Clean Uranium turnings or chips oxidize readily in air.
  • If confined in a container without air movement, they can ignite spontaneously.
  • Moisture increases this reactivity.
  • Uranium turnings stored in water will form a hydride and ignite during warm weather.

Conditions to Avoid:

Radioactive solid that is strongly electropositive. On vigorous shaking the metallic particles exhibit luminescence. It is ductile and malleable and ignites spontaneously in air.

  • May ignite itself if exposed to air.
  • May burn rapidly with flare-burning effect and re-ignite after fire is extinguished.

Incompatible Materials:

  • Chlorine: Violent Reaction.
  • Air: Violent Reaction.
  • Fluorine: Violent Reaction.
  • Nitric Acid: Reacts explosively or with the formation of an explosive surface coating or residue.
  • Nitrogen Oxide: Ignites.
  • Dinitrogen Tetroxide: Explodes or forms an explosive surface coating or residue.
  • Selenium: Reacts violently or incandesces.
  • Sulfur: Reacts violently or incandesces.
  • Water: Violent Reaction Hazard.
  • Ammonia: Reacts violently or incandesces at dull red heat.
  • Bromium Trifluoride: Violent Reaction.
  • Trichloro Ethylene: Violent Reaction.
  • Nitryl Fluoride: Violent Reaction or glowing or white incandescence.
  • Carbon Dioxide: At 750°C Interaction is so rapid that ignition will occur with the finely divided metal, and at 800°C the massive metal will ignite.
  • Carbon Tetrachloride: Use of a carbon tetrachloride fire extinguisher on a small uranium fire led to an explosion.
  • Chlorine: Ignites at 150-180°C.
  • Bromine Vapor: Ignites at 210-240°C.
  • Iodine Vapor: Ignites at 260°C.
  • Acids: Reacts with liberation of hydrogen and formation of salts of tetravalent uranium.

Hazardous Decomposition Products: Thermal decomposition may release toxic and/or hazardous gases.



Carcinogenicity: Contains a radioactive isotope which may produce cancer and genetic mutation.

IARC: No chemical component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by IARC.

NTP: No chemical component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.

OSHA: No chemical component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.

Carcinogen Status: Not carcinogenic as a chemical. Ionizing radiation is carcinogenic.

Health Effects


Radioactive/Nephrotoxin. 30 mg/m3 immediately dangerous to life and health.

Acute Exposure: Uranium may enter the body through inhalation of fine particles that are approximately 1 micron in diameter. Uranium poisoning is characterized by generalized health impairment. It may cause changes in the kidneys, liver, lungs, and cardiovascular, nervous, and hemopoietic systems, and disorders of protein and carbohydrate metabolism. Symptoms may include oliguria, hematuria, albuminuria, and jaundice.

Chronic Exposure: Workers exposed to high average levels of uranium dust in a plant at Oak Ridge have not had increased mortality rates from lung cancer, leukemia, bone cancer, or diseases of the respiratory and genitourinary systems. Lung cancer in uranium miners is probably the result of inhalation of radon daughters found in these mines. Chronic poisoning gives chest findings of pneumoconiosis, pronounced blood changes, and generalized injury. Cancer or lymphatic and blood forming tissues may result. See the following sections regarding the effects of inhalation of an alpha emitter.

Alpha Radiation

Acute Exposure: Alpha radiation is densely ionizing with very high energy and will kill cells immediately adjacent to the source of contact. Damaged cells may not recover or be repaired. Alpha emitters may or may not be absorbed, depending on the solubility and particle size. Insoluble compounds may remain at or near the site of deposition, and soluble compounds may rapidly enter the bloodstream. Heavier particles will be brought up to the throat by ciliary action and may then be swallowed. The lighter particles may be lodged deep in the alveolar air sacs and remain. The damage depends on how quickly they are eliminated, and the susceptibility of the tissue in which they are stored. A single large dose of radiation may lead to increases cancer risk.

Chronic Exposure: The effects of chronic exposure by internally deposited alpha radiation is dependent upon the dose and target organ(a). Possible disorders include lung cancer, sterility, anemia, leukemia, or bone cancer.

The delayed effects of radiation may be due either to a single large overexposure or continuing low-level overexposure and may include cancer, genetic effects, shortening of life span and cataracts. Cancer is observed most frequently in the hematopoietic system, thyroid, bone, and skin. Leukemia is among the most likely forms of malignancy. Lung cancer may also occur due to radioactive materials residing in the lungs. Genetic effects may range from point mutations to severe chromosome damage such as strand breakage, translocations, and deletions. If the germ cells have been affected, the effects of the mutation may not become apparent until the next generation, or even later.

Skin Contact:


Acute Exposure: There is no evidence that insoluble uranium compounds can be absorbed through the skin; insoluble salts produced no signs of poisoning after skin contact. Uranium may irritate the skin.

Chronic Exposure: Prolonged skin contact with insoluble uranium compounds should be avoided because of potential radiation damage to basal cells. Dermatitis has occurred because of handling some insoluble uranium compounds.

Alpha radiation

Acute exposure: Alpha radiation is not usually an external hazard. However, local damage may occur at the site of a wound. Absorption or penetration through damaged skin may result in increased cancer risk.

Chronic exposure: Prolonged or repeated contact my result in increased cancer risk.

Eye Contact:


Acute exposure: Dust may be irritating to the eyes. A variety of soluble and insoluble compounds or uranium were tested on the eyes of rabbits. The insoluble compounds caused the mildest degree of injury. The effects of eye contact with any uranium compound tend to be necrosis of the conjunctivae and eyelids, and ulceration of the cornea.

Chronic exposure: Prolonged exposure to uranium may produce conjunctivitis, or the symptoms of radiation injury, such as cataracts. See the following sections regarding the effects of alpha radiation on the eyes.

Alpha radiation

Acute exposure: Radiation affects the eye by inducing acute inflammation of the conjunctiva and the cornea. The most sensitive part of the eye is the crystalline lens. A late effect of eye irradiation is cataract formation. It may begin anywhere from 6 months to several years after a single exposure. Cataract formation begins at the posterior pole of the lens and continues until the entire lens has been affected. Growth of the opacity may stop at any point. The rate of growth and the degree of opacity are dependent upon the dose of radiation.

Chronic exposure: Repeated or prolonged exposure to alpha radiation may result in cataract formation, as described above. Of the well-documented late effects of radiation on man, leukemia and cataracts have been observed at doses lower than those producing skin scarring and cancer or bone tumors. The lens of the eye should be a critical organ.



Acute exposure: Feeding studies on animals indicate that insoluble uranium is much less toxic than soluble uranium compounds. Uranium entering the bloodstream will become stored in the bone marrow, but the majority will become lodged in the kidney, which is the major site of toxicity. More than a year and a half are required to rid the body of an accidental high dose of uranium, after which time measurable uranium is present in the bone and kidney.

Chronic exposure: The toxic action of uranium resides more in its chemical action on the renal tubules, rather than radiation effects.

Alpha radiation

Acute exposure: The fate of ingested alpha emitters depends on their solubility and valence.

Chronic exposure: Repeated ingestion of alpha emitters may increase cancer risks.

First Aid for Uranium Compounds

Although chelating agents act on uranium, they should not be used because the increased migrant fraction leads through renal precipitation to a greater kidney burden than would be received if there were no treatment at all; there is thus the risk of serious toxic nephritis. The basic treatment should be administration of a bi-carbonated solution given locally and in intravenous perfusion (one bottle of 250 ML at 1.4%).


Environmental Impact Rating (0-4): No data available.

Acute Aquatic Toxicity: No data available.

Degradability: No data available.

Log Bioconcentration Factor (BCF): No data available.

Log Octanol/water partition coefficient: No data available.


Observe all Federal, state, and local regulations when disposing of this substance.


The U.S. Department of Transportation (D.O.T.) Code of Federal Regulations (49 CFR Parts 100-185), the International Air Transportation Association (IATA), International Civil Aviation Organization (ICAO) and International Maritime Organization (IMDG) are all factored into the classification and transport of material.

Proper Shipping Name:

Hazard Class:

UN/ID Number:                                   To be determined on a case-by-case basis.

Special Information:

Packing Group:

Classification of substances with multiple hazards must be determined in accordance with the criteria presented in the regulations mentioned above. Due to the various quantities/combinations of materials being shipped at one time, the information above must be determined based on the characteristics of the specific shipment.



CERCLA SECTION 103 (40 CFR 302.4): N

SARA SECTION 302 (40 CFR 355.30): N

SARA SECTION 304 (40 CFR 355.40): N

SARA SECTION 313 (40 CFR 372.65): N










Copyright 1993 IBI Labs. License granted to make unlimited paper copies for internal use only.

IBI Labs expects that recipients of their material are in compliance with 29 CFR 1910.1200(h) which requires employers to provide employees with effective information and training on hazardous chemicals in their work area.

The information and recommendations set forth herein are presented in good faith and believed to be correct as of the revision date. However, recipients of this material should use this information only as a supplement to other information gathered by them and should make independent judgement of the suitability and accuracy of this information. IBI Labs will not be liable for any special, indirect, incidental, or consequential damages, including but not limited to, loss of any kind whatsoever resulting from the use of the information provided in this Safety Data Sheet. IBI Labs expressly includes all warranties, expressed or implied, including warranties of merchantability and fitness for a particular purpose.

This information is furnished without warranty, and any use of the product not in conformance with this Safety Data Sheet, or in combination with any other product or process, is the responsibility of the user.


    Contact Form

      Your Name (required)

      Your Email (required)

      Please confirm your email (required)

      Your Job/Discipline

      Employer/Work Location


      Phone (required)


      Your Message